|  Publications of Computational BioMedicine Laboratory (CBML)  |  Books


Publications of Computational BioMedicine Laboratory (CBML)

Books (53)


  1. Sakkalis, V. (2015). Modern Electroencephalographic Assessment Techniques: Theory and Applications. Neuromethods series Vol. 91 Springer Science + Business Media, (ISBN 978-1-4939-1298-8).
  2. Tollis, I.G., & Patrignani, M. (2009). Graph Drawing, 16th International Symposium, GD 2008, Heraklion, Crete, Greece, September 21-24, 2008. Revised Papers. Graph DrawingVol. 5417 Springer, (ISBN 978-3-642-00218-2).
  3. Liotta, G., Tamassia, R., & Tollis, I.G. (2006). Graph Algorithms and Applications 4.  World Scientific Publishing.
  4. Liotta, G., Tamassia, R., & Tollis, I.G. (2006). Graph Algorithms and Applications 5.  World Scientific Publishing.
  5. Saranummi, N., Piggott, D., Katehakis, D.G., Tsiknakis, M.N., & Bernstein, K. (2005). Regional Health Economies and ICT Services: The PICNIC Experience.  (pp. i-xi), Vol. 115 IOS Press, (ISBN 978-1-58603-538-9).
  6. Liotta, G., Tamassia, R., & Tollis, I.G. (2004). Graph Algorithms and Applications 2.  World Scientific Publishing.
  7. Liotta, G., Tamassia, R., & Tollis, I.G. (2004). Graph Algorithms and Applications 3.  World Scientific Publishing.

Chapters (in book)

  1. Bonifati, A, Dumbrava , S., & Kondylakis, H. (2020). Graph Summarization.  Springer.
  2. Kanterakis, A., Koumakis, L., Koutoulakis, M., Pitianou, K., Kanakaris, N., Karacapilidis, N., & Potamias, G.A. (2020). An extrovert bioinformatics research object repository and workflow management system. .
  3. Kondylakis, H., Koumakis, L., Mazzocco, K., Tsiknakis, M.N., & Marias, K. (2020). Participatory aspects of ICT infrastructures for cancer management.  (pp. 87 - 108), Cham: Springer.
  4. doi: 10.4018/978-1-5225-8021-8
    Kouroubali, A., Koumakis, L., Kondylakis, H., & Katehakis, D.G. (2019). An Integrated Approach towards Developing Quality Mobile Health Apps for Cancer. January, 2019 IGI Global, (ISBN, doi: 10.4018/978-1-5225-8021-8.
  5. doi: 10.1016/B978-0-12-809414-3.00007-3
    Kanterakis, A., Katsila, T., Potamias, G.A., Patrinos, GP., & Swertz, M.A. (2018). A Review of Tools to Automatically Infer Chromosomal Positions From dbSNP and HGVS Genetic Variants. 2018 (pp. 133 - 156), Elsevier,  doi: 10.1016/B978-0-12-809414-3.00007-3.
  6. doi: 10.1016/B978-0-12-809414-3.00004-8
    Kanterakis, A., Potamias, G.A., & Patrinos, GP. (2018). An Introduction to Tools, Databases, and Practical Guidelines for NGS Data Analysis. 2018 (pp. 61 - 89), Elsevier,  doi: 10.1016/B978-0-12-809414-3.00004-8.
  7. doi: 10.1016/B978-0-12-809414-3.00002-4
    Kanterakis, A., Potamias, G.A., Swertz, M.A., & Patrinos, GP. (2018). Creating Transparent and Reproducible Pipelines: Best Practices for Tools, Data, and Workflow Management Systems. 2018 (pp. 15 - 43), Elsevier,  doi: 10.1016/B978-0-12-809414-3.00002-4.
  8. doi: 10.1016/b978-0-12-802971-8.00019-5
    Koumakis, L., Mizzi, C., & Potamias, G.A. (2017). Bioinformatics Tools for Data Analysis. In Molecular Diagnostics .  (pp. 339 - 351), Elsevier,  doi: 10.1016/b978-0-12-802971-8.00019-5.
  9. doi: 10.1007/978-1-4614-7163-9_110171-1
    Stefanidis, K., Ntoutsi, E, Kondylakis, H., & Velegrakis, Y. (2017). Social-based Collaborative Filtering. Encyclopedia of Social Network Analysis and Mining (ESNAM). 23 June 2017 (pp. 1 - 9), Springer,  doi: 10.1007/978-1-4614-7163-9_110171-1.
  10. doi: 10.3233/978-1-61499-653-8-108
    Giannakakis, G., Pediaditis, M., Stavrinidis, G., Konstantinidis, G., Kritsotakis, V., Tsakanikas, V., Ligerakis, M., Sakkalis, V., Vorgia, P., & Tsiknakis, M.N. (2016). A computational platform for continuous seizure anticipitation, monitoring and clinical evaluation.  Vol. 224 (pp. 108 - 113), IOS press, (ISBN 0926-963/1879-8365/ ), doi: 10.3233/978-1-61499-653-8-108.
  11. Manikis, G., Kontopodis, E., Nikiforaki, K., Marias, K., & Papanikolaou, N. (2016). Imaging biomarkers model-based analysis. Imaging Biomarkers: Development and Clinical Integration.  Springer.
  12. Wisniewski, F., Katehakis, D.G., Masi, M., & Bittins, S. (2016). Improving Cross-Border European ePrescription and Patient Summary Services through e-SENS Cross-Sectorial Building Blocks. Global Telemedicine and eHealth Updates: Knowledge ResourcesVol. 9 (pp. 234 - 238), International Society for Telemedicine & eHealth, (ISBN 1998-5509).
  13. doi:
    Karacapilidis, N., & Potamias, G.A. (2016). Towards a Sustainable Solution for Collaborative Healthcare Research.. Innovation in Medicine and Healthcare 2016. 4 June 2016 (pp. 159 - 170), Springer, (Online ISBN: 978-3-319-39687-3, Print ISBN: 978-3-319-39686-6,, doi: .
  14. Manikis, G., Papanikolaou, N., & Matos, C. (2016). Validating the imaging biomarker: the proof of efficacy and effectiveness. Imaging Biomarkers: Development and Clinical Integration.  Springer.
    Marias, K., Nikiforaki, K., Manikis, G., Kontopodis, E., & Papanikolaou, N. (2016). Visualizing tumor environment with perfusion and diffusion MRI: Computational challenges. Computer Graphics International (CGI).  (pp. 113 - 116),
  16. Sakkalis, V., Oikonomou, Th., Tsiaras, V., & Tollis, I.G. (2015). Graph-theoretic indices of evaluating brain network Synchronization: Application in an alcoholism paradigm. Neuromethods seriesVol. 91 (pp. 159 - 169), Springer Science + Business Media, (ISBN 978-1-4939-1298-8).
  17. Koumakis, L., Potamias, G.A., Tsiknakis, M.N., Zervakis, M.E., & Moustakis, V.A. (2015). Integrating Microarray Data and GRNs. Pietro Hiram Guzzi. Microarray Data Analysis, second edition. Methods in Molecular Biology (2014). Springer Protocols. .
  18. Giannakakis, G., Sakkalis, V., Pediaditis, M., & Tsiknakis, M.N. (2015). Methods for Seizure Detection and Prediction: An Overview. NeuromethodsVol. 91 (pp. 131 - 157), Springer New York.
  19. Spanakis, E.G., Sakkalis, V., Marias, K., & Tsiknakis, M.N. (2014). Connection between Biomedical Telemetry and Telemedicine. Handbook of Biomedical Telemetry . 2014/7/17 (pp. 419 - 444).
  20. doi: 10.1007/978-3-642-37893-5_42
    Sakkalis, V., Sfakianakis, S.G., & Marias, K. (2013). Bridging Social Media Technologies and Scientific Research: A Twitter-Enabled Platform for VPH Modeling. Wireless Mobile Communication and Healthcare. MobiHealth 2012. Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications EngineeringVol. 61 Springer, (ISBN 978-3-642-37892-8/978-3-642-37893-5/ ), doi: 10.1007/978-3-642-37893-5_42.
  21. Kondylakis, H., Koumakis, L., Tsiknakis, M.N., Marias, K., Genitsaridi , I., Pravettoni, G, Gorini, A., & Mazzocco, K. (2013). Smart recommendation services in support of patient empowerment and personalized medicine. Multimedia Services in Intelligent Environments – Recommendation Services.  Springer-Verlag.
  22. Katehakis, D.G., Halkiotis, S., & Kouroubali, A. (2012). Materialization of Regional Health Information Networks in Greece: Electronic Health Record Barriers & Enablers.  (pp. 285 - 299), Multi-Science Publishing Company, Texas Tech University, Lubbock, Texas, USA, (ISBN 978-1-907132-39-1).
  23. Marias, K., Sakkalis, V., & Graf, N. (2012). A Framework for Multimodal Imaging Biomarker Extraction with Application to Brain MRIData Mining for Biomarker Discovery. 01-01-2012 Vol. 65 (pp. 91 - 116), Springer Science - Business Media, LLC: Springer US, (ISBN 978-1-4614-2106-1(print)/978-1-4614-2107-8(online)).
  24. Sakkalis, V., & Marias, K. (2012). EEG based biomarker identification using graph-theoretic concepts: Case study in alcoholism. Optimization and Data Analysis in Biomedical Informatics, Fields Institute CommunicationsVol. 63 (pp. 171 - 189), Springer 2012 , (ISBN 978-1-4614-4132-8 ).
  25. Sakkalis, V., & Marias, K. (2012). EEG Based Biomarker Identification Using Graph-Theoretic Concepts: Case Study in AlcoholismFields Institute Communications, Optimization and Data Analysis in Biomedical Informatics2012. 01-01-2012 Vol. 63 (pp. 171 - 189), Springer Science+Business Media New York, (ISBN 10.1007/978-1-4614-4133-5_9).
  26. Hristoskova, A., Sakkalis, V., Zacharioudakis, G., Tsiknakis, M.N., & De Turck, F. (2011). Ontology-Driven Monitoring of Patient’s Vital Signs Enabling Personalized Medical Detection and Alert. Lecture Notes of the Institute for Computer Sciences, Social Informatics and Telecommunications Engineering (LNICST)Vol. 83 (pp. 217 - 224), Springer 2012, (ISBN 978-3-642-29733-5).
  27. Sakkalis, V., & Zervakis, M.E. (2010). Linear and Nonlinear Synchronization Analysis and Visualization during Altered States of ConsciousnessRecent Advances in Biomedical Engineering.  Vienna: IN-TECH, (ISBN 978-953-307-004-9).
  28. Sakkalis, V., & Zervakis, M.E. (2010). Methodological Framework for EEG Feature Selection based on spectral and temporal profiles. Computational Neuroscience, Springer Optimization and Its Applications seriesVol. 38 Vienna: Springer New York, (ISBN 978-0-387-88629-9).
  29. Dimou, I.N., Zervakis, M.E., Lowe, D., & Tsiknakis, M.N. (2009). Computational Methods and Tools for Decision Support in Biomedicine: An Overview of Algorithmic Challenges. Handbook of Research on Advanced Techniques in Diagnostic Imaging and Biomedical Applications.  (1) (pp. 1 - 17), IGI Global (formerly Idea Group Inc.), (ISBN ISBN13: 9781605663142, ISBN10: 160566314X).
  30. Koumakis, L., Moustakis, V.A., & Potamias, G.A. (2009). Web Services Automation. Handbook of Research on Social Dimensions of Semantic Technologies and Web Services.  IGI Global, (ISBN 1605666505).
  31. Bininda-Emonds, O.R.P., & Stamatakis, A. (2007). Taxon sampling versus computational complexity and their impact on obtaining the Tree of Life. Towards the {T}ree of {L}ife: {T}axonomy and {S}ystematics of {L}arge and {S}pecies-{R}ich {C}lades.  (pp. 77 - 95), CRC Press.
  32. Kouroubali, A., Sakkalis, V., Chronaki, C., & Tsiknakis, M.N. (2006). eChallenges in the Implementation of eHealth Services Over a Hybrid Network Architecture: the case of eLearning. Exploiting the Knowledge Economy: Issues, Applications, Case Studies.  IOS Press, (ISBN 1-58603-682-3).
  33. Katehakis, D.G., & Tsiknakis, M.N. (2006). Electronic Health Record (EHR).  John Wiley & Sons, Inc., (ISBN 0-471-24967-X, May 2006).
  34. Tsiknakis, M.N. (2006). The HYGEIAnet experiences on adoption of innovations and change management. Network For Future Regional Health Care, Transforming Health Care Organisations.  (pp. 31 - 46), Helsinki University Press, (ISBN 952-10-3494-7).
  35. Traganitis, A.P., Spanakis, E.G., & Orphanoudakis, S.C. (2006). Wireless Communication Technologies for Mobile Healthcare Applications: Experiences and Evaluation of Security Related Issues. M-Health: Emerging Mobile Health Systems.  (15) (pp. 65 - 80), Springer US, (ISBN 978-0-387-26558-2 (Print) 978-0-387-26559-9 (Online)).
  36. Tsiknakis, M.N., & Saranummi, N. (2005). Lessons Learned from PICNIC. Regional Health Economies and ICT Services: The PICNIC ExperienceVol. 115 (pp. 215 - 228), Netherlands, (ISBN 0926-9630).
  37. Orphanoudakis, S.C., & Marias, K. (2005). Physics and Modern Technology in Medicine:From X-rays to Nuclear Magnetic Resonance (in greek). Physics Today. The Ten Scales of Matter (in Greek)Vol. II Crete, Greece: Cretan University Press, (ISBN 960-7309-08-1).
  38. Katehakis, D.G., Bruun-Rasmussen, M., Pakarinen, V., Piggott, D., & Saranummi, N. (2005). PICNIC TechnologyRegional Health Economies and ICT Services: The PICNIC ExperienceVol. 115 (pp. 61 - 91), Netherlands, (ISBN 0926-9630 (Print)).
  39. Katehakis, D.G. (2005). The PICNIC StoryRegional Health Economies and ICT Services: The PICNIC ExperienceVol. 115 (pp. 4 - 36), IOS Press, (ISBN 978-1-58603-538-9).
  40. Kouroubali, A., Detmer, D.E., Tsiknakis, M.N., & Orphanoudakis, S.C. (2004). A Health Care Information System in Greece: Key Factors, Self-Organization, and Take-Home Lessons.  (ISBN 978-0-7879-7105-2).

Edited Proceedings

  1. Antoniou, G., Potamias, G.A., Spyropoulos, C., & Plexousakis, D. (2006). Advances in Artificial Intelligence, 4th Helenic Conference on AI, SETN 2006, Heraklion, Crete, Greece, May 18-20, 2006, Proceedings. SETN; Lecture Notes in Computer ScienceVol. 3955 Springer, (ISBN 3-540-34117-X).


  1. Marias, K. (2021). The constantly evolving role of medical image processing in oncology: From traditional medical image processing to imaging biomarkers and Radiomics . 07/2021 (pp. 124), Vol. 7(8) Multidisciplinary Digital Publishing Institute, J. Imaging,

Authored Chapters in books and encyclopedias

  1. Katehakis, D.G., & Kouroubali, A. (2021). Digital Transformation Challenges for the Development of Quality Electronic Medical Records in GreeceIn “Quality of Healthcare in the Aftermath of the COVID-19 Pandemic”. December 2021 (pp. 112-134), Hershey, PA, USA: IGI Global,  DOI: 10.4018/978-1-7998-9198-7.ch007.
  2. Katehakis, D.G., & Kouroubali, A. (2020). Digital Transformation Challenges for the Implementation of Quality Electronic Medical Records. January (pp. 63-91), Hershey, PA, USA: “Quality Assurance in the Era of Individualized Medicine”, IGI Global,  DOI: 10.4018/978-1-7998-2390-2.ch003, S2CID: 209065798.
  3. Katehakis, D.G., Pangalos, G., & Prentza, A. (2020). Security Improvements for Safer Cross-Border E-Health Services in Europe. January (pp. 257-281), Hershey, PA, USA: In “Quality Assurance in the Era of Individualized Medicine”, IGI Global,  DOI: 10.4018/978-1-7998-2390-2.ch010, S2CID: 211758481.
  4. Katehakis, D.G. (2019). Electronic Medical Record Implementation Challenges for the National Health System in Greece. December (pp. 1450-1466), Hershey, PA, USA: In Data Analytics in Medicine: Concepts, Methodologies, Tools, and Applications (4 Volumes), Information Resources Management Association (an imprint of IGI Global),  DOI: 10.4018/978-1-7998-1204-3.ch072.
Found: 53 publications